PROCESS FOR HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS

Quinolone carboxylic esters of general formula (II) are hydrolyzed to form quinolone carboxylic acids of general formula (I): the method comprises the step A): A) reacting compounds of formula (II) with a mixture that comprises acetic acid, sulfuric acid and water. In step A), >= 30 to = 0.3 to =...

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Hauptverfasser: WIRTHS JORG, BERWE MATHIAS, WISCHNAT RALF, LONGERICH MARKUS, DIETZEL ANTJE, FEY PETER
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Quinolone carboxylic esters of general formula (II) are hydrolyzed to form quinolone carboxylic acids of general formula (I): the method comprises the step A): A) reacting compounds of formula (II) with a mixture that comprises acetic acid, sulfuric acid and water. In step A), >= 30 to = 0.3 to = 0.9 to