Pan-cancer detection panel based on next-generation sequencing technology and application of detection panel

The invention belongs to the technical field of pan-cancer polygene detection and discloses a pan-cancer detection panel based on a next-generation sequencing technology. Important exon regions and partial intron regions of 141 genes are enriched by utilizing a gene probe hybridization method, so that accurate detection is achieved; and more importantly, a detection object is patient DNA, and ctDNA is combined with a gene panel to serve as an examination object, so that targeted detection can be realized, and the gene detection cost of a patient and the operation difficulty of an experimentercan be reduced. Meanwhile, a polygene screening list is made into a probe, and high-risk genes are detected in a targeted mode through hybridization capture sequencing, so that gene mutation with guiding significance for diagnosis and treatment can be detected more efficiently, and meanwhile certain tumor patients can be helped to participate in clinical trials. The pan-cancer detection panel hasimportant guiding signific