Preparation method of cefoperazone sodium and tazobactam sodium for injection

The invention discloses a preparation method of cefoperazone sodium and tazobactam sodium for injection. The method comprises the following steps of S1, performing raw medicine screening: crushing andscreening the raw medicines cefoperazone sodium and tazobactam sodium to obtain the raw medicines with the particle size of 150-200 meshes; S2, mixing the materials: mixing the screened cefoperazonesodium and tazobactam sodium in proportion in a mixer, and blowing gas into the mixer in the mixing process, with the temperature of the gas is 25-30 DEG C and the relative humidity is 25%-30%; S3, after it is detected that the materials are uniformly mixed, storing the mixed materials in an aluminum barrel for later use; and S4, sub-packaging the mixed materials into injection reagent bottles ina sterile mode, and performing plug pressing and cap pricking sequentially. According to the method, particle size screening is carried out on the raw medicines, and reasonable particle size is combined with the process of blow