Preparation method and use method of thermal response dual-network hydrogel dressing

The invention provides a preparation method of a thermal response dual-network hydrogel dressing; the prepared hydrogel dressing is composed of two parts, namely a fragile and rigid physical cross-linked network as a reversible switch and a soft and flexible chemical cross-linked network. The OSG is...

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Hauptverfasser: XIE RUIQI, LU FEI, YU KUN, HU ENLING, MAO QIN, LAN GUANGQIAN
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creator XIE RUIQI
LU FEI
YU KUN
HU ENLING
MAO QIN
LAN GUANGQIAN
description The invention provides a preparation method of a thermal response dual-network hydrogel dressing; the prepared hydrogel dressing is composed of two parts, namely a fragile and rigid physical cross-linked network as a reversible switch and a soft and flexible chemical cross-linked network. The OSG is successfully prepared by introducing Schiff base (-N=C) into a polymer structure as a reticular point; due to the successful introduction of the shape memory net point, the OSG shows an effective thermal response shape memory characteristic when Ttrans (38 DEG C) is close to a physiological temperature. The OSG hydrogel disclosed by the invention has enough mechanical capacity and histocompatibility for wound healing, promotes wound tissue remodeling, and can self-contract attached skin from aslender shape after thermal stimulation so as to noninvasively close an incision. The OSG disclosed by the invention is simple in use method, is an attractive suture substitute, and has a wide marketprospect. 本发明提供一种热响应双网络水凝胶
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subjects AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
GENERAL PROCESSES OF COMPOUNDING
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
WORKING-UP
title Preparation method and use method of thermal response dual-network hydrogel dressing
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