Application of galactotetraose sulfate and derivatives thereof in preparation of drugs for resisting epithelial cell adhesion

The invention provides application of galactotetraose sulfate and derivatives thereof in preparation of drugs for resisting epithelial cell adhesion. The galactotetraose sulfate or the derivatives thereof are applied to the drugs for resisting the epithelial cell adhesion, or the galactotetraose sul...

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Bibliographische Detailangaben
Hauptverfasser:	DU YANXIAO, WANG FENGJUAN, LI XIA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The invention provides application of galactotetraose sulfate and derivatives thereof in preparation of drugs for resisting epithelial cell adhesion. The galactotetraose sulfate or the derivatives thereof are applied to the drugs for resisting the epithelial cell adhesion, or the galactotetraose sulfate or the derivatives thereof are applied to a functional food for resisting the epithelial cell adhesion. The galactotetraose sulfate can achieve target binding with focal adhesion kinas (FAK). In this way, the adhesion capability of epithelial cells is effectively inhibited. 本发明提供了硫酸半乳四糖及其衍生物在制备抗上皮细胞黏附药物中的应用。将所述硫酸半乳四糖或者所述硫酸半乳四糖衍生物应用于抗上皮细胞黏附的药物，或者将所述硫酸半乳四糖或者所述硫酸半乳四糖衍生物应用于抗上皮细胞黏附的功能食品。所述硫酸半乳四糖能靶向结合斑激酶(FAK)；有效抑制上皮细胞的黏附能力。