PROCESS TO REDUCE ENDOTOXIN IN GELATIN

The present disclosure is directed to processes for reducing the endotoxin level in gelatin and the resulting gelatin with low endotoxin content. The process includes dissolving a salt in a gelatin solution and filtering the gelatin-salt solution using anion exchange to reduce the endotoxin level. A...

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Bibliographische Detailangaben
Hauptverfasser: HITCHING AMI, SHIRKHANI KHOJASTEH, WONG YIK TENG, STEWART SARAH
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure is directed to processes for reducing the endotoxin level in gelatin and the resulting gelatin with low endotoxin content. The process includes dissolving a salt in a gelatin solution and filtering the gelatin-salt solution using anion exchange to reduce the endotoxin level. After reducing the endotoxin level of the gelatin-salt solution, the low endotoxin gelatin-salt solution is desalted to remove the salt, thereby producing a low endotoxin gelatin solution. 本公开涉及用于降低明胶中内毒素水平的方法和所得的具有低内毒素含量的明胶。方法包括使盐溶于明胶溶液,并用阴离子交换过滤明胶-盐溶液,以降低内毒素水平。在降低明胶-盐溶液的内毒素水平后,使低内毒素明胶-盐溶液脱盐,以去除盐,从而产生低内毒素明胶溶液。