Application of stem cell-derived microvesicles in preparation of preparation for repairing scars
The invention provides application of stem cell-derived microvesicles in preparation of a preparation for repairing scars, and relates to the technical field of scar skin repair. In the invention, theextracellular vesicles derived from the mesenchymal stem cells obviously inhibit the expression of c...
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| creator | LI YING'AO JIA QINGZHI ZHANG BIN BIE QINGLI WU PEIPEI WEI DONG CHEN YANRONG GAN LIJUN BAN BO XIE NA |
| description | The invention provides application of stem cell-derived microvesicles in preparation of a preparation for repairing scars, and relates to the technical field of scar skin repair. In the invention, theextracellular vesicles derived from the mesenchymal stem cells obviously inhibit the expression of collagen III, the collagen III in the treatment group of the high-concentration microvesicles and the low-concentration microvesicles is obviously lower than that in the PBS group, and the expression of collagen I also presents a decreasing trend; both the high-concentration microvesicles and the low-concentration microvesicles can promote reasonable distribution of a skin structure, specifically, the structure of collagen is more reasonable, and accessory structures are remarkably increased; therefore, the stem cell-derived microvesicles have a scar repairing effect, the low-concentration microvesicles and the high-concentration microvesicles can promote the repairing effect of scar skin, the scar area of the repai |
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In the invention, theextracellular vesicles derived from the mesenchymal stem cells obviously inhibit the expression of collagen III, the collagen III in the treatment group of the high-concentration microvesicles and the low-concentration microvesicles is obviously lower than that in the PBS group, and the expression of collagen I also presents a decreasing trend; both the high-concentration microvesicles and the low-concentration microvesicles can promote reasonable distribution of a skin structure, specifically, the structure of collagen is more reasonable, and accessory structures are remarkably increased; therefore, the stem cell-derived microvesicles have a scar repairing effect, the low-concentration microvesicles and the high-concentration microvesicles can promote the repairing effect of scar skin, the scar area of the repai</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201106&DB=EPODOC&CC=CN&NR=111888379A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201106&DB=EPODOC&CC=CN&NR=111888379A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI YING'AO</creatorcontrib><creatorcontrib>JIA QINGZHI</creatorcontrib><creatorcontrib>ZHANG BIN</creatorcontrib><creatorcontrib>BIE QINGLI</creatorcontrib><creatorcontrib>WU PEIPEI</creatorcontrib><creatorcontrib>WEI DONG</creatorcontrib><creatorcontrib>CHEN YANRONG</creatorcontrib><creatorcontrib>GAN LIJUN</creatorcontrib><creatorcontrib>BAN BO</creatorcontrib><creatorcontrib>XIE NA</creatorcontrib><title>Application of stem cell-derived microvesicles in preparation of preparation for repairing scars</title><description>The invention provides application of stem cell-derived microvesicles in preparation of a preparation for repairing scars, and relates to the technical field of scar skin repair. 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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS |
| title | Application of stem cell-derived microvesicles in preparation of preparation for repairing scars |
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