Application of borneol in preparation of brain glioma radiotherapy combined medicine

The invention relates to the field of tumor drugs, and discloses an application of borneol in preparation of a brain glioma radiotherapy combined drug. The inventor of the invention finds that borneolcan effectively enhance the sensitivity of malignant brain glioma radiotherapy, and the effect may be that the expression of HIF1a is regulated and controlled by mediating mTORC1/eIF4E signaling pathways so as to reverse radiotherapy resistance, so that borneol can be used as a malignant brain glioma radiotherapy combined drug. 本发明涉及肿瘤药物领域，公开了冰片在制备脑胶质瘤放疗联合药物中的应用。本发明发现了冰片可有效增强恶性脑胶质瘤放疗的敏感性，该作用可能是通过介导mTORC1/eIF4E信号通路调控HIF-1a表达进而逆转放疗抵抗，因此可将冰片作为恶性脑胶质瘤放疗联合药物使用。