ANTI-CD33 AND ANTI-CD7 COMBINATION TREATMENT

This invention relates to the dual targeting of cell inhibiting agents to the cell surface receptors CD7 and CD33 in the treatment of hematological malignancy. In particular, the invention relates tocell inhibiting agents that bispecifically binds to CD33 and CD7 for use in the treatment of a CD7+CD...

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creator DANIELS TIFFANY JANE
description This invention relates to the dual targeting of cell inhibiting agents to the cell surface receptors CD7 and CD33 in the treatment of hematological malignancy. In particular, the invention relates tocell inhibiting agents that bispecifically binds to CD33 and CD7 for use in the treatment of a CD7+CD33+ hematological malignancy. Such agents may comprise bispecific antibody drug conjugates. 本发明涉及在恶性血液肿瘤的治疗中使细胞抑制剂双重靶向细胞表面受体CD7和CD33。特别地,本发明涉及用于治疗CD7+CD33+恶性血液肿瘤的双特异性结合CD33和CD7的细胞抑制剂。此种试剂可以包含双特异性抗体药物缀合物。
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Such agents may comprise bispecific antibody drug conjugates. 本发明涉及在恶性血液肿瘤的治疗中使细胞抑制剂双重靶向细胞表面受体CD7和CD33。特别地,本发明涉及用于治疗CD7+CD33+恶性血液肿瘤的双特异性结合CD33和CD7的细胞抑制剂。此种试剂可以包含双特异性抗体药物缀合物。</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20201030&amp;DB=EPODOC&amp;CC=CN&amp;NR=111868087A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20201030&amp;DB=EPODOC&amp;CC=CN&amp;NR=111868087A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DANIELS TIFFANY JANE</creatorcontrib><title>ANTI-CD33 AND ANTI-CD7 COMBINATION TREATMENT</title><description>This invention relates to the dual targeting of cell inhibiting agents to the cell surface receptors CD7 and CD33 in the treatment of hematological malignancy. 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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTI-CD33 AND ANTI-CD7 COMBINATION TREATMENT
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