ANTI-CD33 AND ANTI-CD7 COMBINATION TREATMENT

This invention relates to the dual targeting of cell inhibiting agents to the cell surface receptors CD7 and CD33 in the treatment of hematological malignancy. In particular, the invention relates tocell inhibiting agents that bispecifically binds to CD33 and CD7 for use in the treatment of a CD7+CD...

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Bibliographische Detailangaben
1. Verfasser:	DANIELS TIFFANY JANE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to the dual targeting of cell inhibiting agents to the cell surface receptors CD7 and CD33 in the treatment of hematological malignancy. In particular, the invention relates tocell inhibiting agents that bispecifically binds to CD33 and CD7 for use in the treatment of a CD7+CD33+ hematological malignancy. Such agents may comprise bispecific antibody drug conjugates. 本发明涉及在恶性血液肿瘤的治疗中使细胞抑制剂双重靶向细胞表面受体CD7和CD33。特别地，本发明涉及用于治疗CD7+CD33+恶性血液肿瘤的双特异性结合CD33和CD7的细胞抑制剂。此种试剂可以包含双特异性抗体药物缀合物。