Vero monoclonal cell line and application thereof

The invention discloses a Vero monoclonal cell line and application thereof, and belongs to the field of virus culture and vaccine preparation. The Vero monoclonal cell line Vero-TB of the invention is extremely sensitive to PRRSV, and the proliferation efficiency of the PRRSV in the Vero-TB is much...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN LIQUN, XING GANG, YUE FENGXIONG, HUANG JIE, LIU YUANZI, PAN QIAN, LIU XIAORONG, CHEN QIU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a Vero monoclonal cell line and application thereof, and belongs to the field of virus culture and vaccine preparation. The Vero monoclonal cell line Vero-TB of the invention is extremely sensitive to PRRSV, and the proliferation efficiency of the PRRSV in the Vero-TB is much higher than that in Marc-145. The PRRSV cultured with Vero-TB can be applied to PRRS vaccine preparation, with good safety and effectiveness. In short, the cell line of the invention has a very good application prospect. 本发明公开了一株Vero单克隆细胞系及其应用，属于病毒培养和疫苗制备领域。本发明的Vero单克隆细胞系Vero-TB对PRRSV极其敏感，后者在Vero-TB中的增殖效率远高于在Marc-145中的增殖效率。将Vero-TB培养的PRRSV可用于制备PRRS疫苗，其安全性和有效性俱佳。总之，本发明的细胞系具有十分良好的应用前景。