Application of periplaneta americana extract CII-3 in attenuated synergistic antitumor drug cisplatin

The invention provides an application of a periplaneta americana extract CII-3 in an attenuated synergistic antitumor drug cisplatin, and relates to the technical field of attenuated synergists. The attenuated synergist is prepared from a periplaneta americana extract CII-3. A Lewis lung cancer tumor-bearing mouse model is used for testing, and it is found that CII-3 has a synergistic and attenuated effect on a DDP treatment of lewis lung cancer tumor-bearing mouse; the attenuated synergist CII-3 disclosed by the invention has an improvement effect on myelosuppression of a DDP treatment of Lewis lung cancer tumor-bearing mouse; CII-3 can improve the hematopoietic system of Lewis lung cancer tumor-bearing mice after DDP treatment; the improvement action mechanism of CII-3 in combination with DDP on treatment of Lewis lung cancer tumor-bearing mouse myelosuppression is related to up-regulation of the expression of G-CSF, GM-CSF mRNA and corresponding proteins in bone marrow tissues. 本发明提供了美洲大蠊提取物CII-3在减毒增效抗肿瘤药物