Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles
The invention provides composite magnetic particles, a method for removing red blood cells in peripheral blood or bone marrow cells and application of the composite magnetic particles, and relates tothe technical field of specific cell separation. The surface of each composite magnetic particle is c...
Gespeichert in:
Hauptverfasser: | , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | XU LONGFEI CHENG LANLING LI YANTAO HE SUN LI JUNHUI GAO DOU SHI XIAOXIAO WANG ZUNBAO ZHANG WEI |
description | The invention provides composite magnetic particles, a method for removing red blood cells in peripheral blood or bone marrow cells and application of the composite magnetic particles, and relates tothe technical field of specific cell separation. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody for specifically identifying an erythrocyte surface antigen. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody capable of specifically recognizing red blood cell surface antigen,therefore, red blood cells in peripheral blood or bone marrow cells can be specifically adsorbed and removed through antigen-antibody reaction, the problems that an existing method for removing the red blood cells in the bone marrow cells is complex in process and high in preparation cost are effectively solved, and the method can be widely applied to the preparation process of the mononuclear cells.
本发明提供了一种复合磁性微粒、去除外周血或骨 |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN111808811A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN111808811A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN111808811A3</originalsourceid><addsrcrecordid>eNqNjTEOwjAMRbswIOAOZgeJiKUrqoqYmNgrN3XbSE5sJRHchdMSpM6I6X35P9vr6t2IV0kuE3icAmVnQTEWMKUDeMqzDDBKhEheni5MJQzQs5SxJeYELoBSdDpTRF6a4vcSvjdjlNciYhgAVdlZzE4CyAj2x_dttRqRE-0Wbqr9tX00tyOpdJQULZWNrrkbY-pTXRtzOf_jfAA3tlNX</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles</title><source>esp@cenet</source><creator>XU LONGFEI ; CHENG LANLING ; LI YANTAO ; HE SUN ; LI JUNHUI ; GAO DOU ; SHI XIAOXIAO ; WANG ZUNBAO ; ZHANG WEI</creator><creatorcontrib>XU LONGFEI ; CHENG LANLING ; LI YANTAO ; HE SUN ; LI JUNHUI ; GAO DOU ; SHI XIAOXIAO ; WANG ZUNBAO ; ZHANG WEI</creatorcontrib><description>The invention provides composite magnetic particles, a method for removing red blood cells in peripheral blood or bone marrow cells and application of the composite magnetic particles, and relates tothe technical field of specific cell separation. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody for specifically identifying an erythrocyte surface antigen. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody capable of specifically recognizing red blood cell surface antigen,therefore, red blood cells in peripheral blood or bone marrow cells can be specifically adsorbed and removed through antigen-antibody reaction, the problems that an existing method for removing the red blood cells in the bone marrow cells is complex in process and high in preparation cost are effectively solved, and the method can be widely applied to the preparation process of the mononuclear cells.
本发明提供了一种复合磁性微粒、去除外周血或骨</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201023&DB=EPODOC&CC=CN&NR=111808811A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201023&DB=EPODOC&CC=CN&NR=111808811A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>XU LONGFEI</creatorcontrib><creatorcontrib>CHENG LANLING</creatorcontrib><creatorcontrib>LI YANTAO</creatorcontrib><creatorcontrib>HE SUN</creatorcontrib><creatorcontrib>LI JUNHUI</creatorcontrib><creatorcontrib>GAO DOU</creatorcontrib><creatorcontrib>SHI XIAOXIAO</creatorcontrib><creatorcontrib>WANG ZUNBAO</creatorcontrib><creatorcontrib>ZHANG WEI</creatorcontrib><title>Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles</title><description>The invention provides composite magnetic particles, a method for removing red blood cells in peripheral blood or bone marrow cells and application of the composite magnetic particles, and relates tothe technical field of specific cell separation. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody for specifically identifying an erythrocyte surface antigen. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody capable of specifically recognizing red blood cell surface antigen,therefore, red blood cells in peripheral blood or bone marrow cells can be specifically adsorbed and removed through antigen-antibody reaction, the problems that an existing method for removing the red blood cells in the bone marrow cells is complex in process and high in preparation cost are effectively solved, and the method can be widely applied to the preparation process of the mononuclear cells.
本发明提供了一种复合磁性微粒、去除外周血或骨</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTEOwjAMRbswIOAOZgeJiKUrqoqYmNgrN3XbSE5sJRHchdMSpM6I6X35P9vr6t2IV0kuE3icAmVnQTEWMKUDeMqzDDBKhEheni5MJQzQs5SxJeYELoBSdDpTRF6a4vcSvjdjlNciYhgAVdlZzE4CyAj2x_dttRqRE-0Wbqr9tX00tyOpdJQULZWNrrkbY-pTXRtzOf_jfAA3tlNX</recordid><startdate>20201023</startdate><enddate>20201023</enddate><creator>XU LONGFEI</creator><creator>CHENG LANLING</creator><creator>LI YANTAO</creator><creator>HE SUN</creator><creator>LI JUNHUI</creator><creator>GAO DOU</creator><creator>SHI XIAOXIAO</creator><creator>WANG ZUNBAO</creator><creator>ZHANG WEI</creator><scope>EVB</scope></search><sort><creationdate>20201023</creationdate><title>Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles</title><author>XU LONGFEI ; CHENG LANLING ; LI YANTAO ; HE SUN ; LI JUNHUI ; GAO DOU ; SHI XIAOXIAO ; WANG ZUNBAO ; ZHANG WEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111808811A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>XU LONGFEI</creatorcontrib><creatorcontrib>CHENG LANLING</creatorcontrib><creatorcontrib>LI YANTAO</creatorcontrib><creatorcontrib>HE SUN</creatorcontrib><creatorcontrib>LI JUNHUI</creatorcontrib><creatorcontrib>GAO DOU</creatorcontrib><creatorcontrib>SHI XIAOXIAO</creatorcontrib><creatorcontrib>WANG ZUNBAO</creatorcontrib><creatorcontrib>ZHANG WEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>XU LONGFEI</au><au>CHENG LANLING</au><au>LI YANTAO</au><au>HE SUN</au><au>LI JUNHUI</au><au>GAO DOU</au><au>SHI XIAOXIAO</au><au>WANG ZUNBAO</au><au>ZHANG WEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles</title><date>2020-10-23</date><risdate>2020</risdate><abstract>The invention provides composite magnetic particles, a method for removing red blood cells in peripheral blood or bone marrow cells and application of the composite magnetic particles, and relates tothe technical field of specific cell separation. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody for specifically identifying an erythrocyte surface antigen. The surface of each composite magnetic particle is coupled with a monoclonal antibody or a polyclonal antibody capable of specifically recognizing red blood cell surface antigen,therefore, red blood cells in peripheral blood or bone marrow cells can be specifically adsorbed and removed through antigen-antibody reaction, the problems that an existing method for removing the red blood cells in the bone marrow cells is complex in process and high in preparation cost are effectively solved, and the method can be widely applied to the preparation process of the mononuclear cells.
本发明提供了一种复合磁性微粒、去除外周血或骨</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | chi ; eng |
recordid | cdi_epo_espacenet_CN111808811A |
source | esp@cenet |
subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | Composite magnetic particles, method for removing red blood cells in peripheral blood or bone marrow cells and application of composite magnetic particles |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T05%3A15%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=XU%20LONGFEI&rft.date=2020-10-23&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN111808811A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |