Saponin compound as well as preparation method and application thereof
The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, conc...
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| creator | LEI HOUXING CHEN LIPING ZHANG XIAOQIN LIN NA |
| description | The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, concentrating the leaching solution, adding water to prepare a water suspension; extracting the water suspension, concentrating the extract to obtain an extract; and separating and purifying the extract to obtain the saponin compound. The saponin compound with a novel structure is separated and identified from rubus hirsutus, has wide pharmacological activity, and can be used for preparing antitumor drugs, tumor prevention health-care foods, anti-tyrosinase drugs or whitening cosmetics.
本发明公开了一种皂苷化合物及其制备方法与应用；所述皂苷化合物为hirsutuside A。该化合物的提取方法为：将蓬蘽置于有机溶剂中浸提，得到浸提液，将浸提液浓缩后加水制备水混悬液；对水混悬液进行萃取，将萃取液浓缩，获得浸膏；从浸膏中分离纯化得到所述皂苷化合物；本发明从蓬蘽中分离鉴定了一种具有新颖结构的皂苷化合物，具有广泛的药理活性，能用于制备抗肿瘤药物或肿瘤预防保健食品、抗酪氨酸酶药物或美白化妆品。 |
| format | Patent |
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本发明公开了一种皂苷化合物及其制备方法与应用；所述皂苷化合物为hirsutuside A。该化合物的提取方法为：将蓬蘽置于有机溶剂中浸提，得到浸提液，将浸提液浓缩后加水制备水混悬液；对水混悬液进行萃取，将萃取液浓缩，获得浸膏；从浸膏中分离纯化得到所述皂苷化合物；本发明从蓬蘽中分离鉴定了一种具有新颖结构的皂苷化合物，具有广泛的药理活性，能用于制备抗肿瘤药物或肿瘤预防保健食品、抗酪氨酸酶药物或美白化妆品。</description><language>chi ; eng</language><subject>CHEMISTRY ; FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS ; STEROIDS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201016&DB=EPODOC&CC=CN&NR=111777657A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201016&DB=EPODOC&CC=CN&NR=111777657A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEI HOUXING</creatorcontrib><creatorcontrib>CHEN LIPING</creatorcontrib><creatorcontrib>ZHANG XIAOQIN</creatorcontrib><creatorcontrib>LIN NA</creatorcontrib><title>Saponin compound as well as preparation method and application thereof</title><description>The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, concentrating the leaching solution, adding water to prepare a water suspension; extracting the water suspension, concentrating the extract to obtain an extract; and separating and purifying the extract to obtain the saponin compound. The saponin compound with a novel structure is separated and identified from rubus hirsutus, has wide pharmacological activity, and can be used for preparing antitumor drugs, tumor prevention health-care foods, anti-tyrosinase drugs or whitening cosmetics.
本发明公开了一种皂苷化合物及其制备方法与应用；所述皂苷化合物为hirsutuside A。该化合物的提取方法为：将蓬蘽置于有机溶剂中浸提，得到浸提液，将浸提液浓缩后加水制备水混悬液；对水混悬液进行萃取，将萃取液浓缩，获得浸膏；从浸膏中分离纯化得到所述皂苷化合物；本发明从蓬蘽中分离鉴定了一种具有新颖结构的皂苷化合物，具有广泛的药理活性，能用于制备抗肿瘤药物或肿瘤预防保健食品、抗酪氨酸酶药物或美白化妆品。</description><subject>CHEMISTRY</subject><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><subject>STEROIDS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHALTizIz8vMU0jOzy3IL81LUUgsVihPzckB0QVFqQWJRYklmfl5CrmpJRn5QFmQioKCnMxkiHBJRmpRan4aDwNrWmJOcSovlOZmUHRzDXH20E0tyI9PLS5ITE7NSy2Jd_YzNDQ0Nzc3MzV3NCZGDQBCzjPU</recordid><startdate>20201016</startdate><enddate>20201016</enddate><creator>LEI HOUXING</creator><creator>CHEN LIPING</creator><creator>ZHANG XIAOQIN</creator><creator>LIN NA</creator><scope>EVB</scope></search><sort><creationdate>20201016</creationdate><title>Saponin compound as well as preparation method and application thereof</title><author>LEI HOUXING ; CHEN LIPING ; ZHANG XIAOQIN ; LIN NA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111777657A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</topic><topic>STEROIDS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LEI HOUXING</creatorcontrib><creatorcontrib>CHEN LIPING</creatorcontrib><creatorcontrib>ZHANG XIAOQIN</creatorcontrib><creatorcontrib>LIN NA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEI HOUXING</au><au>CHEN LIPING</au><au>ZHANG XIAOQIN</au><au>LIN NA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Saponin compound as well as preparation method and application thereof</title><date>2020-10-16</date><risdate>2020</risdate><abstract>The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, concentrating the leaching solution, adding water to prepare a water suspension; extracting the water suspension, concentrating the extract to obtain an extract; and separating and purifying the extract to obtain the saponin compound. The saponin compound with a novel structure is separated and identified from rubus hirsutus, has wide pharmacological activity, and can be used for preparing antitumor drugs, tumor prevention health-care foods, anti-tyrosinase drugs or whitening cosmetics.
本发明公开了一种皂苷化合物及其制备方法与应用；所述皂苷化合物为hirsutuside A。该化合物的提取方法为：将蓬蘽置于有机溶剂中浸提，得到浸提液，将浸提液浓缩后加水制备水混悬液；对水混悬液进行萃取，将萃取液浓缩，获得浸膏；从浸膏中分离纯化得到所述皂苷化合物；本发明从蓬蘽中分离鉴定了一种具有新颖结构的皂苷化合物，具有广泛的药理活性，能用于制备抗肿瘤药物或肿瘤预防保健食品、抗酪氨酸酶药物或美白化妆品。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS STEROIDS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Saponin compound as well as preparation method and application thereof |
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