Saponin compound as well as preparation method and application thereof

The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, conc...

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Hauptverfasser: LEI HOUXING, CHEN LIPING, ZHANG XIAOQIN, LIN NA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a saponin compound as well as a preparation method and application thereof. The saponin compound is hirsutuside A. The extraction method of the compound comprises the followingsteps: putting rubus hirsutus in an organic solvent for leaching to obtain a leaching solution, concentrating the leaching solution, adding water to prepare a water suspension; extracting the water suspension, concentrating the extract to obtain an extract; and separating and purifying the extract to obtain the saponin compound. The saponin compound with a novel structure is separated and identified from rubus hirsutus, has wide pharmacological activity, and can be used for preparing antitumor drugs, tumor prevention health-care foods, anti-tyrosinase drugs or whitening cosmetics. 本发明公开了一种皂苷化合物及其制备方法与应用;所述皂苷化合物为hirsutuside A。该化合物的提取方法为:将蓬蘽置于有机溶剂中浸提,得到浸提液,将浸提液浓缩后加水制备水混悬液;对水混悬液进行萃取,将萃取液浓缩,获得浸膏;从浸膏中分离纯化得到所述皂苷化合物;本发明从蓬蘽中分离鉴定了一种具有新颖结构的皂苷化合物,具有广泛的药理活性,能用于制备抗肿瘤药物或肿瘤预防保健食品、抗酪氨酸酶药物或美白化妆品。