Preparation method and application of papaya total triterpenes hydrogel

The invention discloses preparation and application of papaya total triterpenes hydrogel. The papaya total triterpenes hydrogel is prepared from papaya total triterpenes, methoxy-polyethylene glycol,epsilon-caprolactone and alpha-cyclodextrin, and the prepared hydrogel is applied to application of promoting skin wound healing. The preparation method comprises the specific steps of taking mPEG andepsilon-CL as substrates, under catalysis of diethyl etherate hydrochloride, carrying out ring-opening polymerization reaction on epsilon-CL and mPEG, and synthesizing mPEG-polycaprolactone with a hydrophilic chain segment and a hydrophobic chain segment; then, taking mPEG-PCL as a material, and preparing the papaya total triterpenes drug-loaded micelle through a thin film hydration method; and uniformly mixing the papaya total triterpenes drug-loaded micelle and alpha-CD on a vortex mixer to obtain the papaya total triterpenes hydrogel. The method provided by the invention has the advantagesof simple process and easi