Phenoxybenzylamine hydrochloride tablets and preparation method thereof

The invention discloses a phenoxybenzylamine hydrochloride tablet which comprises the following components: phenoxybenzylamine hydrochloride, dextrin, pregelatinized starch, a disintegrating agent, afilling agent, an adhesive, a lubricating agent and a flow aid. The viscosity of the dextrin ranges from 4.5 mpa.s to 8.5 mpa.s; the specific surface area of the pregelatinized starch is less than orequal to 350m < 2 >/kg; the disintegrating agent is carboxymethyl starch sodium. A disintegrating agent such as carboxymethyl starch sodium, dextrin with viscosity of 4.5-8.5 mpa.s and pregelatinizedstarch with specific surface area of less than or equal to 350m < 2 >/kg are added into the components, so that the obtained phenoxybenzamine hydrochloride tablet has improved dissolution rate and dissolution rate uniformity, and is small in intra-group difference and good in stability. 本发明公开了一种盐酸酚苄明片剂，其组分包括：盐酸酚苄明、糊精、预胶化淀粉、崩解剂、填充剂、粘合剂、润滑剂和助流剂。所述糊精的粘度为4.5-8.5mpa.s；所述预胶化淀粉比表面积≤350m2/kg；所述崩解剂是羧甲淀粉钠。在组分中加入崩解剂如羧甲淀粉钠和粘度为4.5-8.5mp