Monoclonal neutralizing antibody of HPV52L1 and application of monoclonal neutralizing antibody
The invention relates to the technical field of antibody drugs, in particular to a monoclonal neutralizing antibody of HPV52L1 and an application thereof. The invention provides a specific monoclonalneutralizing antibody of HPV52 and a hybridoma cell line of generating the antibody. One monoclonal n...
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| creator | WEI YINGYING SONG GAOSHANG GUO GUANGHUA SHEN JIANGWEI ZOU GUOBAO LIN HAO LIU XINXIN |
| description | The invention relates to the technical field of antibody drugs, in particular to a monoclonal neutralizing antibody of HPV52L1 and an application thereof. The invention provides a specific monoclonalneutralizing antibody of HPV52 and a hybridoma cell line of generating the antibody. One monoclonal neutralizing antibody with the highest neutralization activity titer can be widely applied to detection of HPV52 virus infection in clinical samples by using an indirect ELISA method, a double-antibody sandwich ELISA method, an immunological hybridization method and the like; and the monoclonal neutralizing antibody with the highest neutralization activity titer can be used to prepare a vaginal gel, a vaginal cleaning fluid, a topical lotion, a vaginal suppository, freeze-dried powder, a vaginaleffervescent tablet and the like, is applied to treatment of HPV52 infection patients and can effectively improve the clinical negative conversion rate of the HPV52 patients. The monoclonal neutralizing antibody is of great s |
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The invention provides a specific monoclonalneutralizing antibody of HPV52 and a hybridoma cell line of generating the antibody. One monoclonal neutralizing antibody with the highest neutralization activity titer can be widely applied to detection of HPV52 virus infection in clinical samples by using an indirect ELISA method, a double-antibody sandwich ELISA method, an immunological hybridization method and the like; and the monoclonal neutralizing antibody with the highest neutralization activity titer can be used to prepare a vaginal gel, a vaginal cleaning fluid, a topical lotion, a vaginal suppository, freeze-dried powder, a vaginaleffervescent tablet and the like, is applied to treatment of HPV52 infection patients and can effectively improve the clinical negative conversion rate of the HPV52 patients. 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| language | chi ; eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | Monoclonal neutralizing antibody of HPV52L1 and application of monoclonal neutralizing antibody |
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