Method for testing efficacy of porcine Seneca virus disease inactivated vaccine by using rabbits

The invention discloses a method for testing the efficacy of a porcine Seneca virus disease inactivated vaccine by using rabbits, and belongs to the field of veterinary biological products. The methodcomprises the following steps: performing immunization on a plurality of healthy susceptible rabbits...

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Hauptverfasser: ZHAO LIXIA, QI ZHITAO, ZHANG YANHONG, LI XUEFENG, LU RONG, GAO YANHUA, WANG E'E, ZHANG YUNXING, SONG QINGQING, BI LIGE, CHEN JIULIAN, FANG JIANGUO, DU YURONG, HAO SUYUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a method for testing the efficacy of a porcine Seneca virus disease inactivated vaccine by using rabbits, and belongs to the field of veterinary biological products. The methodcomprises the following steps: performing immunization on a plurality of healthy susceptible rabbits by using the porcine Seneca virus disease inactivated vaccine; after 28 days of immunization, performing virus attack on the immunized rabbits by using a Seneca virus solution; and after virus attack, continuously observing for 15 days, and when at least 4/5 of the rabbits do not show clinical symptoms after virus attack, judging that the protection efficacy of the porcine Seneca virus disease inactivated vaccine is qualified. According to the method, the rabbits can be effectively used for replacing experimental pigs to establish a replacement method for testing the efficacy of the Seneca virus disease inactivated vaccine, so that the cost is effectively reduced; and the method is simpleand feasible to operate, s