Application of American cockroach extract skimmed cream in DDP, anti-tumor medicine for toxicity reduction and efficacy enhancement

The invention provides application of American cockroach extract skimmed cream in DDP, an anti-tumor medicine for toxicity reduction and efficacy enhancement and relates to the technical field of agents for toxicity reduction and efficacy enhancement. The agent for toxicity reduction and efficacy en...

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Hauptverfasser: HE MIAO, LIU XIAOBO, HUANG YAYA, LIU GUANGMING, LI CHENGGONG, SHI MILI, PENG FANG, LIU HENG, HE ZHENGCHUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides application of American cockroach extract skimmed cream in DDP, an anti-tumor medicine for toxicity reduction and efficacy enhancement and relates to the technical field of agents for toxicity reduction and efficacy enhancement. The agent for toxicity reduction and efficacy enhancement comprises an American cockroach extract, wherein the American cockroach extract is skimmedcream. The effect of toxicity reduction and efficacy enhancement of the American cockroach extract skimmed cream is manifested in restraining transfer of cachexia cancer cells in lungs by combining the DDP; relieving liver damage caused by the DDP; prolonging survival time of a Lewis lung cancer mouse; recovering a lung index and a thymus index of the mouse, which are reduced by the DDP; recovering a B lymphocyte proliferation capacity reduced by the DDP; and recovering the NK cell killing activity reduced by the DDP. Marrow depression caused when the agent for toxicity reduction and efficacyenhancement is combined w