Monoclonal neutralizing antibody of HPV18L1 and application of monoclonal neutralizing antibody

The invention relates to the technical field of antibody drugs, in particular to a monoclonal neutralizing antibody of HPV18L1 and application of the monoclonal neutralizing antibody. The invention provides a specific monoclonal neutralizing antibody of HPV18 and a hybridoma cell line for producing the antibody. The monoclonal neutralizing antibody with the highest neutralizing activity titer canbe widely applied to infection detection of HPV18 virus in a clinical sample by adopting an indirect ELISA method, a double-antibody sandwich ELISA method, an immune hybridization method and the like;and the monoclonal neutralizing antibody with the highest neutralizing activity titer is used for preparing vaginal gel, vaginal cleaning fluid, external lotion, vaginal suppository, freeze-dried powder, vaginal effervescent tablets and the like, is used for treating HPV18 infected patients, and can effectively improve the clinical negative conversion ratio of the HPV18 patients. The monoclonal neutralizing antibody is of