Method for synthesis of beta-adrenomimetic excitant type fodder additive

The process for synthesizing Ractopamine Hydrochloride as feed additive includes oximation and catalytic hydrogenation of Fructus rubi ketone to obtain 1-methyl-3-(4-hydroxyl phenyl)-propylamine, reaction of omega-bromo-p-hydoxyl acetophenone, 1-methyl-3-(4-hydroxylphenyl)-propylamine with triethyla...

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Hauptverfasser: MI AIQIAO, CHEN DAIMO, JIANG YAOZHONG
Format: Patent
Sprache:eng
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Zusammenfassung:The process for synthesizing Ractopamine Hydrochloride as feed additive includes oximation and catalytic hydrogenation of Fructus rubi ketone to obtain 1-methyl-3-(4-hydroxyl phenyl)-propylamine, reaction of omega-bromo-p-hydoxyl acetophenone, 1-methyl-3-(4-hydroxylphenyl)-propylamine with triethylamine in tetrahydrofuran to obtain hydrochloric salt of 1-(4-hydroxylphenyl)-2- 1-methyl-3(4-hydroxylphenyl) propylamino¨-methylketone, and hydrogenation.