Multifunctional injectable hydrogel for tumor photo-thermal treatment and bone tissue repair and preparation method

The invention discloses multifunctional injectable hydrogel for tumor photo-thermal treatment and bone tissue repair and a preparation method, and belongs to the field of biomedical materials. The preparation method comprises the following steps of firstly, synthesizing micro-nano carbon spheres by...

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Hauptverfasser: WU CHENGWEI, MA JIANLI, WEI CHENGXIONG, JIN XIN, ZHANG WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses multifunctional injectable hydrogel for tumor photo-thermal treatment and bone tissue repair and a preparation method, and belongs to the field of biomedical materials. The preparation method comprises the following steps of firstly, synthesizing micro-nano carbon spheres by adopting a hydrothermal carbonization method; secondly, adding the micro-nano carbon spheres into achitosan solution, and performing uniform stirring to obtain a solution A; thirdly, simultaneously dissolving beta-sodium glycerophosphate and sodium hyaluronate in deionized water, and performing sufficient stirring to obtain a solution B; and finally, in an ice bath environment, adding the solution B into the solution A, uniformly stirring the solutions, and performing sterilizing and disinfection for 24 hours by using an ultraviolet lamp to obtain the injectable composite hydrogel. The injectable hydrogel has good biocompatibility; the injectable hydrogel is in a liquid state at the room temperature, can be directl