Alkoxy carbonyl substituted silicon-based rhodamine derivative, preparation method and application thereof

The invention discloses an alkoxy carbonyl substituted silicon-based rhodamine derivative, a preparation method and application thereof, wherein the alkoxy carbonyl substituted silicon-based rhodaminederivative is prepared by carrying out a heating tube sealing reaction on a silicon-based intermediate and alkoxy carbonyl substituted o-formylbenzoic acid in the absence of a solvent in the presenceof a catalyst. According to the invention, the synthesis method of the silicon-based rhodamine derivative provided by the invention is simple in reaction condition, convenient to operate and high intotal yield, and can be used for large-scale preparation; and the silicon-based rhodamine derivative reacts under an alkaline condition, can be used for efficiently preparing the carboxyl-substitutedsilicon-based rhodamine derivative, and is used for preparing various fluorescent dyes and probes. 本发明公开了一种烷氧基羰基取代硅基罗丹明衍生物及其制备方法与应用。所述烷氧基羰基取代硅基罗丹明衍生物是通过硅基中间体与烃氧基羰基取代邻醛基苯甲酸在无溶剂条件下，在催化剂存在时，加热封管反应制备得到。本发明提供的硅基罗丹明衍生物合成方法反应条件简单，操作方便，