Application of tilianin in preparation of medicine for improving expression of LXR-alpha

The invention discloses an application of tilianin in preparation of a medicine for improving expression of LXR-alpha, which belongs to the technical field of medicines, discloses a method for determining regulation and control of tilianin in LXR-alpha expression by taking H9c2 myocardial cell hypox...

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Hauptverfasser: DILINUER AILIAJI, ZHENG RUIFANG, DU YANWEN, XING JIANGUO, YU NING, REZIYAMU WUFUER
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an application of tilianin in preparation of a medicine for improving expression of LXR-alpha, which belongs to the technical field of medicines, discloses a method for determining regulation and control of tilianin in LXR-alpha expression by taking H9c2 myocardial cell hypoxia/reoxygenation (H/R) injury as a model and taking LXR-alpha as a molecular target, and provides abasis for searching and developing medicines for effectively preventing and treating cardiovascular and cerebrovascular diseases. 本发明公开了田蓟苷在制备提高LXR-α的表达的药物中的应用,属于医药技术领域,以H9c2心肌细胞缺氧/复氧(H/R)损伤为模型,以LXR-α作为分子靶标,确定了田蓟苷在LXR-α表达中的调控,为寻找开发有效地防治心脑血管疾病的药物提供了依据。