Synthesis method of 5-hydroxymethyl furfural-Enulosides compound

The invention discloses a synthetic method of a 5-hydroxymethyl furfural-Enulosides compound. The preparation method is characterized by comprising the following steps: taking fully acylated and fullybenzoylated glycoene as a donor; using 5-hydroxymethylfurfural as a receptor; carrying out a Ferrier...

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Hauptverfasser: ZHANG JIANBO, DONG YOUXIAN, JIANG NAN, MEI YULING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a synthetic method of a 5-hydroxymethyl furfural-Enulosides compound. The preparation method is characterized by comprising the following steps: taking fully acylated and fullybenzoylated glycoene as a donor; using 5-hydroxymethylfurfural as a receptor; carrying out a Ferrier rearrangement reaction under the catalysis of Fe3O4@C@Al, removing a protecting group from theprepared 5-hydroxymethylfurfural 2, 3-unsaturated glucoside compound, and carrying out selective oxidation on allyl hydroxyl to prepare the HMF-Enuloside compound with a single [alpha] configuration.Compared with the prior art, the method has the advantages of the simple synthesis process, convenience in operation, high product selectivity and the like; and the used magnetic catalyst is convenient to recover, can be recycled for many times, still has high catalytic activity, the high yield and low production cost, and is an efficient stereoselective synthesis method which is green, environment-friendly, economic and e