PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE

Process for preparation of Enzalutamide using novel intermediate. Provided herein is a process for the preparation of a novel [4-cyano-3- (trifluoromethyl)phenyl]carbamodithioic acid and its use in preparation of Enzalutamide being cost effective with higher yield, higher HPLC purity with reduced im...

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Bibliographische Detailangaben
Hauptverfasser:	KAMBLE KIRAN MOHAN, NIKAM VIKAS HIRAMAN, DESAI PARIMAL HASMUKHLAL, SEETHARAMAN SUBRAMANIAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Process for preparation of Enzalutamide using novel intermediate. Provided herein is a process for the preparation of a novel [4-cyano-3- (trifluoromethyl)phenyl]carbamodithioic acid and its use in preparation of Enzalutamide being cost effective with higher yield, higher HPLC purity with reduced impurities. 本文提供的使用新中间体来制备恩杂鲁胺的方法是一种用于制备新[4-氰基-3-(三氟甲基)苯基]氨基二硫代甲酸的方法及其在制备恩杂鲁胺中的用途，该方法由于具有更高的产率、杂质减少的更高HPLC纯度而具有成本效益。