Esters of dihydrotetrabenazine

The present invention relates to a compound of formula (I) including any stereochemically isomeric form thereof, or a pharmaceutically acceptable salt thereof, wherein R1 is -C(=O)O-alkyl, carbonate ester, or -C(=O)-alkyl, ester, or -C(=O)N-alkyl, carbamate ester, and R2 is -CH3 or -CD3. The alkyl ester can contain the saturated or unsaturated C12 to C26 alkyl carbon. The alkyl carbon chain can have either a straight, branched, noncyclic, cyclic, unsubstituted or substituted structure. 本发明涉及一种式(I)化合物，包括其任何立体化学异构形式或其药学上可接受的盐。其中R为-C(═O)O-烷基碳酸酯或-C(═O)-烷基酯或-C(═O)N-烷基氨基甲酸酯，并且其中R为-CH或-CD。烷基酯可以含有饱和或不饱和C-C烷基碳。烷基碳链可以具有直链、支链、非环状、环状、未经取代或经取代结构。