Preparation method and application of chitosan-sodium alginate hydrogel

The invention provides a preparation method and an application of chitosan-sodium alginate hydrogel. The chitosan-sodium alginate hydrogel provided by the invention is used as a medicine carrying carrier, and has the characteristics of simple synthesis method, high encapsulation efficiency and high crosslinking degree, the carrier hydrogel has a two-phase group having a high affinity for a livingbody, the sodium alginate has acid decomposition resistance, chitosan is automatically degraded in an acidic environment, sodium alginate enables the chitosan-sodium alginate hydrogel to be slowly unlinked under a meta-acidic condition to release internally loaded drugs, the action time of the drugs is prolonged, the action effect of the drugs is improved, and it is indicated that the chitosan-sodium alginate hydrogel has wide substantive application as a new drug-loading carrier hydrogel. 本发明提供了一种壳聚糖-海藻酸钠水凝胶的制备和应用，本发明提供的壳聚糖-海藻酸钠水凝胶作为载药载体，具有合成方法简单、包封率高，交联度高等特点，本发明的载体水凝胶具有对生物体亲和性高的两相基团，海藻酸钠具有抗酸性分解的性能，壳聚糖在酸性环境中自动降解，海藻酸钠