Gel as well as complete set of raw materials and application thereof

The invention relates to gel as well as a complete set of raw materials and application thereof. The gel is obtained by blending a first solution and a second solution and then carrying out in-situ cross-linking, a first component contained in the first solution is aldehyde group modified polysaccha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WU LIANGLIANG, WAN WENQIAN, CAO BIN, ZHU JIAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to gel as well as a complete set of raw materials and application thereof. The gel is obtained by blending a first solution and a second solution and then carrying out in-situ cross-linking, a first component contained in the first solution is aldehyde group modified polysaccharide, and a second component contained in the second solution is composed of hydrazide-based small molecules and hydrazide-based modified polysaccharide. The complete set of raw materials is composed of the first component and the second component. The gel provided by the invention is suitable for tissue engineering applications such as vitreous body replacement gel, ocular surface sealing gel, fundus sealing gel and the like. 本发明涉及一种凝胶、其成套原料及应用。该凝胶由第一溶液与第二溶液共混后原位交联获得,第一溶液含有的第一组分为醛基改性多糖,第二溶液含有的第二组分由酰肼基小分子、酰肼基改性多糖构成。该成套原料由第一组分和第二组分构成。本发明的凝胶适用于玻璃体替代凝胶、眼表封闭胶、眼底封闭胶等组织工程应用。