USE OF SYNCYTIN FOR TARGETING DRUG AND GENE DELIVERY TO REGENERATING MUSCLE TISSUE

The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to regenerating muscle tissue, comprising at least a therapeutic drug or gene, associated to asyncytin protein, and its use in the prevention and/or treatment of muscle injuries or diseases, in...

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Hauptverfasser: FERRAND MAXIME, GALY ANNE
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creator FERRAND MAXIME
GALY ANNE
description The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to regenerating muscle tissue, comprising at least a therapeutic drug or gene, associated to asyncytin protein, and its use in the prevention and/or treatment of muscle injuries or diseases, in particular in gene therapy of said diseases using lentiviral vector particles or lentivirus-like particles pseudotyped with syncytin protein. 本发明涉及将药物靶向递送(包括基因递送)至再生肌肉组织的药物组合物,其至少包含与合胞素蛋白结合的治疗性药物或基因,及其在预防和/或治疗肌肉损伤或疾病中的用途,特别是在使用用合胞素蛋白假型化的慢病毒载体颗粒或慢病毒样颗粒基因治疗所述疾病中的用途。
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title USE OF SYNCYTIN FOR TARGETING DRUG AND GENE DELIVERY TO REGENERATING MUSCLE TISSUE
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