PHARMACEUTICAL FORMULATIONS COMPRISING OPIOID RECEPTOR AGONIST AS ACTIVE INGREDIENTS, METHODS OF MANUFACTURE AND THERAPEUTIC USES THEREOF

The present invention concerns a pharmaceutical formulation in form of aqueous solution for sublingual and buccal administration, for the treatment of neonatal abstinence syndrome, said formulation comprising buprenorphine or a pharmaceutically acceptable salt thereof as the sole active ingredient,...

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Hauptverfasser: CAIVANO GRAZIA, SILVA BORGES ANA FILIPA
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SILVA BORGES ANA FILIPA
description The present invention concerns a pharmaceutical formulation in form of aqueous solution for sublingual and buccal administration, for the treatment of neonatal abstinence syndrome, said formulation comprising buprenorphine or a pharmaceutically acceptable salt thereof as the sole active ingredient, a viscosity enhancer, and a buffering agent in an amount to provide a pH of from 5.0 to 7.0. 本发明涉及用于舌下和含服施用的呈水溶液形式的药物制剂,其用于治疗新生儿戒断综合征,所述制剂包含丁丙诺啡或其药学上可接受的盐作为唯一活性成分、粘度增强剂和提供5.0-7.0的pH的量的缓冲剂。
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PHARMACEUTICAL FORMULATIONS COMPRISING OPIOID RECEPTOR AGONIST AS ACTIVE INGREDIENTS, METHODS OF MANUFACTURE AND THERAPEUTIC USES THEREOF
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