METHOD AND APPARATUS TO MITIGATE EVAPORATION IN HIGH THROUGHPUT MEASUREMENTS

A method and apparatus are disclosed for the collection of light scattered from a liquid sample contained within a multiwell plate for which evaporation from the wells is mitigated by the applicationof a barrier between the liquid sample and the environment. A vertical thermal gradient is applied across the vessel so that condensation is inhibited from forming on the interior surface of the barrier, thus permitting clear illumination of the sample for visual imaging, fluorescence studies and light scattering detection. 公开了用于收集从多孔板内容纳的液体样品散射的光的方法和设备，其中通过在液体样品和环境之间施加屏障来减缓液体样品从孔蒸发。跨越容器施加竖直热梯度以抑制凝结在屏障的内表面上形成，从而允许对样品进行清晰的照明以进行视觉成像、荧光研究和光散射检测。