Preparation method of 24-hydroxy-stearyl glycyrrhetinate

The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yiel...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YUAN JIANGHUA, ZHANG YUEHONG, ZHOU SHOUCHAO, ZHOU YANYAN, FAN JUNYAN, HUANG XIAOXIN, ZHOU HAICHAO, CHENG YUANBIN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator YUAN JIANGHUA
ZHANG YUEHONG
ZHOU SHOUCHAO
ZHOU YANYAN
FAN JUNYAN
HUANG XIAOXIN
ZHOU HAICHAO
CHENG YUANBIN
description The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yield of effective substances is high, and resources are fully utilized; compared with 24-hydroxy-glycyrrhetinic acid, the prepared 24-hydroxy-stearyl glycyrrhetinic acid ester has the advantages that the lipophilic higher alkanol is introduced, so that the solubility in grease is obviously changed; meanwhile, compared with 24-hydroxy-glycyrrhetinic acid, the anti-inflammatory effect is better, and the 24-hydroxy-stearyl glycyrrhetinic acid ester is suitable for large-scale popularization and application. 一种24-羟基硬脂醇甘草亭酸酯的制备方法,涉及食品、化妆品、医药、保健品领域,本发明以甘草甜味素为原料,提取工艺简单,可操作性强;有效物质得率高,充分利用资源;制备的24-羟基-硬脂醇甘草亭酸酯与24-羟基-甘草次酸相比,由于导入了亲油性的高级烷醇,在油脂内溶解性得到了显著的改变,同时相对于24-羟基-甘草次酸抗炎效果更好,适合大范围的推广和应用。
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN111171106A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN111171106A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN111171106A3</originalsourceid><addsrcrecordid>eNrjZLAIKEotSCxKLMnMz1PITS3JyE9RyE9TMDLRzahMKcqvqNQtLklNLKrMUUjPqUyuLCrKSC3JzEssSeVhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoZAYG5oaGDmaEyMGgArhi6Z</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation method of 24-hydroxy-stearyl glycyrrhetinate</title><source>esp@cenet</source><creator>YUAN JIANGHUA ; ZHANG YUEHONG ; ZHOU SHOUCHAO ; ZHOU YANYAN ; FAN JUNYAN ; HUANG XIAOXIN ; ZHOU HAICHAO ; CHENG YUANBIN</creator><creatorcontrib>YUAN JIANGHUA ; ZHANG YUEHONG ; ZHOU SHOUCHAO ; ZHOU YANYAN ; FAN JUNYAN ; HUANG XIAOXIN ; ZHOU HAICHAO ; CHENG YUANBIN</creatorcontrib><description>The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yield of effective substances is high, and resources are fully utilized; compared with 24-hydroxy-glycyrrhetinic acid, the prepared 24-hydroxy-stearyl glycyrrhetinic acid ester has the advantages that the lipophilic higher alkanol is introduced, so that the solubility in grease is obviously changed; meanwhile, compared with 24-hydroxy-glycyrrhetinic acid, the anti-inflammatory effect is better, and the 24-hydroxy-stearyl glycyrrhetinic acid ester is suitable for large-scale popularization and application. 一种24-羟基硬脂醇甘草亭酸酯的制备方法,涉及食品、化妆品、医药、保健品领域,本发明以甘草甜味素为原料,提取工艺简单,可操作性强;有效物质得率高,充分利用资源;制备的24-羟基-硬脂醇甘草亭酸酯与24-羟基-甘草次酸相比,由于导入了亲油性的高级烷醇,在油脂内溶解性得到了显著的改变,同时相对于24-羟基-甘草次酸抗炎效果更好,适合大范围的推广和应用。</description><language>chi ; eng</language><subject>CHEMISTRY ; FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS ; STEROIDS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200519&amp;DB=EPODOC&amp;CC=CN&amp;NR=111171106A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200519&amp;DB=EPODOC&amp;CC=CN&amp;NR=111171106A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YUAN JIANGHUA</creatorcontrib><creatorcontrib>ZHANG YUEHONG</creatorcontrib><creatorcontrib>ZHOU SHOUCHAO</creatorcontrib><creatorcontrib>ZHOU YANYAN</creatorcontrib><creatorcontrib>FAN JUNYAN</creatorcontrib><creatorcontrib>HUANG XIAOXIN</creatorcontrib><creatorcontrib>ZHOU HAICHAO</creatorcontrib><creatorcontrib>CHENG YUANBIN</creatorcontrib><title>Preparation method of 24-hydroxy-stearyl glycyrrhetinate</title><description>The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yield of effective substances is high, and resources are fully utilized; compared with 24-hydroxy-glycyrrhetinic acid, the prepared 24-hydroxy-stearyl glycyrrhetinic acid ester has the advantages that the lipophilic higher alkanol is introduced, so that the solubility in grease is obviously changed; meanwhile, compared with 24-hydroxy-glycyrrhetinic acid, the anti-inflammatory effect is better, and the 24-hydroxy-stearyl glycyrrhetinic acid ester is suitable for large-scale popularization and application. 一种24-羟基硬脂醇甘草亭酸酯的制备方法,涉及食品、化妆品、医药、保健品领域,本发明以甘草甜味素为原料,提取工艺简单,可操作性强;有效物质得率高,充分利用资源;制备的24-羟基-硬脂醇甘草亭酸酯与24-羟基-甘草次酸相比,由于导入了亲油性的高级烷醇,在油脂内溶解性得到了显著的改变,同时相对于24-羟基-甘草次酸抗炎效果更好,适合大范围的推广和应用。</description><subject>CHEMISTRY</subject><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><subject>STEROIDS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAIKEotSCxKLMnMz1PITS3JyE9RyE9TMDLRzahMKcqvqNQtLklNLKrMUUjPqUyuLCrKSC3JzEssSeVhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoZAYG5oaGDmaEyMGgArhi6Z</recordid><startdate>20200519</startdate><enddate>20200519</enddate><creator>YUAN JIANGHUA</creator><creator>ZHANG YUEHONG</creator><creator>ZHOU SHOUCHAO</creator><creator>ZHOU YANYAN</creator><creator>FAN JUNYAN</creator><creator>HUANG XIAOXIN</creator><creator>ZHOU HAICHAO</creator><creator>CHENG YUANBIN</creator><scope>EVB</scope></search><sort><creationdate>20200519</creationdate><title>Preparation method of 24-hydroxy-stearyl glycyrrhetinate</title><author>YUAN JIANGHUA ; ZHANG YUEHONG ; ZHOU SHOUCHAO ; ZHOU YANYAN ; FAN JUNYAN ; HUANG XIAOXIN ; ZHOU HAICHAO ; CHENG YUANBIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111171106A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</topic><topic>STEROIDS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>YUAN JIANGHUA</creatorcontrib><creatorcontrib>ZHANG YUEHONG</creatorcontrib><creatorcontrib>ZHOU SHOUCHAO</creatorcontrib><creatorcontrib>ZHOU YANYAN</creatorcontrib><creatorcontrib>FAN JUNYAN</creatorcontrib><creatorcontrib>HUANG XIAOXIN</creatorcontrib><creatorcontrib>ZHOU HAICHAO</creatorcontrib><creatorcontrib>CHENG YUANBIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YUAN JIANGHUA</au><au>ZHANG YUEHONG</au><au>ZHOU SHOUCHAO</au><au>ZHOU YANYAN</au><au>FAN JUNYAN</au><au>HUANG XIAOXIN</au><au>ZHOU HAICHAO</au><au>CHENG YUANBIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of 24-hydroxy-stearyl glycyrrhetinate</title><date>2020-05-19</date><risdate>2020</risdate><abstract>The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yield of effective substances is high, and resources are fully utilized; compared with 24-hydroxy-glycyrrhetinic acid, the prepared 24-hydroxy-stearyl glycyrrhetinic acid ester has the advantages that the lipophilic higher alkanol is introduced, so that the solubility in grease is obviously changed; meanwhile, compared with 24-hydroxy-glycyrrhetinic acid, the anti-inflammatory effect is better, and the 24-hydroxy-stearyl glycyrrhetinic acid ester is suitable for large-scale popularization and application. 一种24-羟基硬脂醇甘草亭酸酯的制备方法,涉及食品、化妆品、医药、保健品领域,本发明以甘草甜味素为原料,提取工艺简单,可操作性强;有效物质得率高,充分利用资源;制备的24-羟基-硬脂醇甘草亭酸酯与24-羟基-甘草次酸相比,由于导入了亲油性的高级烷醇,在油脂内溶解性得到了显著的改变,同时相对于24-羟基-甘草次酸抗炎效果更好,适合大范围的推广和应用。</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN111171106A
source esp@cenet
subjects CHEMISTRY
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
STEROIDS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title Preparation method of 24-hydroxy-stearyl glycyrrhetinate
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T13%3A04%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YUAN%20JIANGHUA&rft.date=2020-05-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN111171106A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true