Preparation method of 24-hydroxy-stearyl glycyrrhetinate

The invention discloses a preparation method of 24-hydroxy-stearyl glycyrrhetinate, and relates to the field of foods, cosmetics, medicines and health-care products. In the method, glycyrrhizin is used as a raw material, so that the extraction process is simple, and the operability is high; the yield of effective substances is high, and resources are fully utilized; compared with 24-hydroxy-glycyrrhetinic acid, the prepared 24-hydroxy-stearyl glycyrrhetinic acid ester has the advantages that the lipophilic higher alkanol is introduced, so that the solubility in grease is obviously changed; meanwhile, compared with 24-hydroxy-glycyrrhetinic acid, the anti-inflammatory effect is better, and the 24-hydroxy-stearyl glycyrrhetinic acid ester is suitable for large-scale popularization and application. 一种24-羟基硬脂醇甘草亭酸酯的制备方法，涉及食品、化妆品、医药、保健品领域，本发明以甘草甜味素为原料，提取工艺简单，可操作性强；有效物质得率高，充分利用资源；制备的24-羟基-硬脂醇甘草亭酸酯与24-羟基-甘草次酸相比，由于导入了亲油性的高级烷醇，在油脂内溶解性得到了显著的改变，同时相对于24-羟基-甘草次酸抗炎效果更好，适合大范围的推广和应用。