Synthesis method of 2-aryl benzoxazole derivative

The invention discloses a synthesis method of a 2-aryl benzoxazole derivative, wherein the method comprises the steps: carrying out ultrasonic reaction on an o-nitrophenol derivative and an aryl formaldehyde derivative in the presence of a pyridine accelerator and an elemental sulfur reducing agent to obtain the 2-aryl benzoxazole derivative. The method has the advantages of one-pot reaction synthesis, simple steps, easily available accelerant, low cost, high yield and environmental friendliness, and is beneficial to industrial production and application. 本发明公开了一种2-芳基苯并噁唑衍生物的合成方法，该方法是将邻硝基苯酚衍生物与芳基甲醛衍生物在吡啶促进剂和单质硫还原剂存在下进行超声反应，得到2-芳基苯并噁唑衍生物；该方法一锅反应合成，步骤简单，促进剂易于获得、成本低，收率高，对环境友好，有利于工业化生产应用。