Application of fructus hippophae water-soluble extract for preparing preparation capable of inhibiting phosphorylation of Tau protein

The invention discloses application of a fructus hippophae water-soluble extract for preparing a preparation capable of inhibiting the phosphorylation of a Tau protein. The fructus hippophae water-soluble extract accounts for 20-45 wt% of the preparation capable of inhibiting the phosphorylation of...

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Hauptverfasser: ZHAO HONG, JIAO YINGYING, TANG WEIWEI, ZHANG YU, GAO QI, KONG LINGZHOU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of a fructus hippophae water-soluble extract for preparing a preparation capable of inhibiting the phosphorylation of a Tau protein. The fructus hippophae water-soluble extract accounts for 20-45 wt% of the preparation capable of inhibiting the phosphorylation of the Tau protein. Compared with the prior art, the invention has the following beneficial effects that (1) the phosphorylation of the Tau protein is inhibited so as to prevent and treat the Alzheimer's Disease, a choline inhibitor which is commonly used at present is not adopted, and therefore, no side effects are caused; and (2) through a synergistic effect of all substances, the Alzheimer's Disease is prevented and treated, each medicine independently performs an effect by aiming at the etiology and the pathogenesis of the Alzheimer's Disease and mutually coordinates, a prevention and treatment principle of strengthening the body resistance to eliminate pathogenic factors and addressing both symptoms and root caus