Nano-composite for early diagnosis and treatment of gastric cancer and preparation method of nano-composite

The invention discloses a nano-composite for early diagnosis and treatment of gastric cancer and a preparation method of the nano-composite. The nano-composite has a core-shell structure formed by anamphiphilic copolymer, wherein an inner core layer is formed by a distearoyl phosphatidyl ethanolamine fragment, an outer shell layer is formed by a polyethylene glycol fragment, the inner core layerwraps indocyanine green and a hydrophobic gastric cancer chemotherapeutic drug, and the surface of the outer shell layer is connected with RGD short peptides. The nano-composite preparation integratestargeted gastric cancer treatment and fluorescence imaging tracing, targeted aggregation imaging on gastric cancer focus can be implemented, drug release is controlled, the drug concentration of a targeted site is increased, the drug action time is prolonged, and the nano-composite has a wide application prospect in targeted diagnosis and treatment and drug delivery of early gastric cancer. 本发明公开了一种用于胃癌早期诊断和治疗的纳米复合物及其制备方法。