Compound centella gel preparation, and preparation method and application thereof

The invention belongs to the technical field of compound medicaments, and specifically relates to a compound centella gel preparation, and a preparation method and an application thereof. According tothe invention, after rabbit ear trauma modeling succeeds, a model group, a positive control group an...

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Hauptverfasser: XIANG DONGYANG, YANG ZIZHONG, PENG YIJING, TONG JING, MA NING, LIN YAQIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of compound medicaments, and specifically relates to a compound centella gel preparation, and a preparation method and an application thereof. According tothe invention, after rabbit ear trauma modeling succeeds, a model group, a positive control group and centella gel high-dose, medium-dose and low-dose groups are randomly divided; the positive control group is externally coated with asiaticoside cream; the centella gel high-dose, medium-dose and low-dose groups are externally coated with a high dose, a medium dose and a low dose of the centella gel respectively; the model group is externally coated with the same amount of normal saline; the scar thickness is measured respectively after 14 days and 28 days of treatment to calculate scar hyperplasia indexes; HE staining is made to calculate the number of fibroblasts in scar tissues; Masson staining is made to count the collagen density in the scar tissues; and changes are compared. The curative effect of the compou