Biological patch and preparation method thereof

The invention provides a biological patch. The biological patch is a sheet material mainly consisting of an acelluar matrix. The acelluar matrix is derived from umbilical cord tissue that vascular cells are removed and is mainly formed by the extracellular matrix of the umbilical cord tissue; because the extracellular matrix is rich in various growth factors, the extracellular matrix has good biological activity and can effectively collect the cells of a contact part to provide an appropriate growth structure, and the cells can be induced to perform directed differentiation, so that the healing effects of rotator cuff tissue can be achieved; and in addition, the umbilical cord tissue that the vascular cells are removed is taken as a source, so that the immunogenicity of the biological patch can be effectively reduced, and using safety can be enhanced. A preparation method of the biological patch is also provided. 本发明提供了一种生物补片，所述生物补片是主要由脱细胞基质组成的片状物。所述脱细胞基质来源于去除血管细胞的脐带组织，所述脱细胞基质主要由所述脐带组织的细胞外基质构成，而细胞外基质中因富含多种生长因