(E)-alpha, beta-UNSATURATED AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF

The present invention provides a new class of (E)-alpha, beta-unsaturated amide compounds represented by formula I, and also relates to methods for preparing such compounds and the pharmaceutical usesthereof. The compounds have the effect of protecting nerve cells and an immunoregulatory activity. The definitions of R1, R2 and R3 in formula I are given in the description. 本发明提供一类新的由式I所表示的(E)-α,β-不饱和酰胺化合物，还涉及这类化合物的制备方法及其制药用途。所述化合物具有保护神经细胞的作用和免疫调节活性。式I中R、R和R的定义见说明书。