Preparation capable of improving thermal stability of tablet and kallidinogenase, thermal-stable kallidinogenase tablets and preparation method thereof

The invention relates to a preparation capable of improving thermal stability of a tablet and kallidinogenase, a thermal-stable kallidinogenase tablet and a preparation method thereof, the preparationand kallidinogenase tablet comprise low-moisture microcrystalline cellulose, and the low-moisture microcrystalline cellulose is microcrystalline cellulose with a dry weight loss value of less than orequal to 1.5%. However, through creative research, the low-moisture microcrystalline cellulose can greatly improve the thermal stability of the tablets obtained through direct tabletting, the tabletscan be stored for a long time at the normal temperature and the high temperature, the titer and the purity of the tablets are hardly influenced or slightly influenced, and application is not influenced. For example, in the kallidinogenase tablet, the low-moisture microcrystalline cellulose can improve or ensure the stability of effective components in the kallidinogenase tablet. 本发明涉及一种能够提高片剂、胰激肽原酶热稳定性的制剂以及热稳定的胰激肽原酶片及其制备方法