Synthesis method of difluoroolefin
The invention belongs to the technical field of organic fluorides, and particularly relates to an efficient method for synthesizing difluoroolefin. The method comprises the following steps: 1, takingolefin as an initial raw material, adding an accurately weighed inorganic alkali into a Schlenk react...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the technical field of organic fluorides, and particularly relates to an efficient method for synthesizing difluoroolefin. The method comprises the following steps: 1, takingolefin as an initial raw material, adding an accurately weighed inorganic alkali into a Schlenk reaction tube with a stirrer in a glove box, plugging with a rubber plug, and moving out of the glove box; 2, sucking an organic solvent by using an injector, sucking olefin and ethyl difluoroiodoacetate by using a microsyringe, sequentially adding into the reaction tube, putting into a constant-temperature magnetic stirrer under the irradiation of 30 W blue LED visible light, carrying out a stirring reaction at room temperature, and monitoring the reaction process by using TLC and GC-MS; and 3, after the reaction is finished, taking out the reaction tube, removing the volatile solvent from the reaction solution by using a rotary evaporator under reduced pressure, and purifying by using an eluent through column chromato |
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