Diagnosis and treatment molecule for nervous system diseases

The invention discloses a diagnosis and treatment molecule for nervous system diseases. According to the invention, clinical cases are collected as research objects, up-regulation of expression of HALgenes and expression products thereof in blood of patients is determined by detecting gene expressio...

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Bibliographische Detailangaben
Hauptverfasser:	WANG LIN, ZHANG DONGMEI, SUN YAOLAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a diagnosis and treatment molecule for nervous system diseases. According to the invention, clinical cases are collected as research objects, up-regulation of expression of HALgenes and expression products thereof in blood of patients is determined by detecting gene expression conditions in peripheral blood, Parkinson's disease patients and normal people can be effectivelydistinguished by detecting the HAL genes and the expression products thereof, and a new clinical diagnosis method is provided. The invention also discloses the correlation between HAL and nerve celldamage repair, so that a medicine for treating Parkinson's disease can be developed according to HAL. 本发明公开了一种用于神经系统疾病的诊治分子。本发明收集临床病例作为研究对象，通过检测外周血中基因表达情况，确定了HAL基因及其表达产物在患者血液中表达上调，通过检测HAL基因及其表达产物即可有效区分帕金森病患者和正常人群，为临床提供了一种新的诊断方法。本发明还公开了HAL与神经细胞损伤修复存在相关性，故可根据HAL开发治疗帕金森病的药物。