Preparation method of salazosulfapyridine composition

The invention provides a preparation method of a salazosulfapyridine composition. The preparation method of the salazosulfapyridine composition comprises the following steps: step 1, adding serine hydrazide hydrochloride and a catalyst into an organic solvent, and heating and stirring until the serine hydrazide hydrochloride and the catalyst are completely mixed to obtain a mixed solution; step 2,adding trihydroxybenzaldehyde into the mixed solution obtained in the step 1, and stirring until the trihydroxybenzaldehyde and the mixed solution are uniformly mixed to obtain a precursor solution;step 3, hydrogenating the precursor solution, adding a salazosulfapyridine crude body, mixing, evaporating to remove the organic solvent at a low temperature after hydrogenation is finished, and adding an extracting agent to extract crystals; and step 4, washing the crystal with ethanol or acetone to obtain the salazosulfapyridine composition. The preparation method of the salazosulfapyridine composition is simple in prepa