Application of procyanidin SA hydrogel in preparation of medicine for treating tendon ectopic calcification

The invention discloses an application of procyanidin in regulation and control of stem cell functions in a pathological microenvironment of tendon diseases, and provides a preparation method of procyanidin SA hydrogel and an application of the procyanidin SA hydrogel in treatment of tendon ectopic calcification. Based on the application, the invention proves that: the addition of the procyanidininto tendon stem/progenitor cells does not influence cell proliferation, and can effectively inhibit the calcium deposition of the tendon stem/progenitor cells and the subsequent potential for treating tendon diseases. Through Micro CT, hematoxylin-eosin staining, crocus sativus-solid green staining, collagen II and osteocalcin (OCN) immunohistochemical staining, the situation of the procyanidin SA hydrogel for treating tendon ectopic calcification is detected. The invention finds and proves that the procyanidin SA hydrogel can effectively inhibit tendon ectopic calcification. Meanwhile, the administration route of su