Simple synthesis method of ultra-small Gd2O3 nano particles

The invention relates to a simple synthesis method of ultra-small Gd2O3 nano particles. According to the method, water serves as a solvent, polyvinylpyrrolidone serves as a surfactant and is used forregulating and controlling the particle size, gadolinium oxide nanoparticles are synthesized from gadolinium nitrate under the action of ammonia water, redundant gadolinium ions are removed through dialysis, and therefore the ultra-small Gd2O3 nanoparticles which are good in water dispersibility and wrapped by polyvinylpyrrolidone are obtained. The Gd2O3 nanoparticles synthesized by adopting the method disclosed by the invention have an ultra-small size (less than 5nm), are non-toxic and pollution-free, have good water dispersibility and stability, and have a wide application prospect in the fields of magnetic resonance imaging and biomedicine. 本发明为一种超小GdO纳米颗粒的简易合成方法，该方法以水为溶剂，采用聚乙烯吡咯烷酮为表面活性剂并用于调控颗粒尺寸，利用硝酸钆在氨水作用下合成氧化钆纳米颗粒，通过透析去除多余的钆离子，从而获得水分散性良好、聚乙烯吡咯烷酮包裹的超小GdO纳米颗粒。本发明合成的GdO纳米颗粒具有超小的尺寸（小于5 nm)，且无毒无污染，具有很好的水分散性和稳定性，