AUTOPHAGY INHIBITORS

The present invention provides recombinant peptides useful for inhibiting the function of autophagy-related 8 (Atg8) proteins. The recombinant peptides can be used in the preparation of imaging agentsfor monitoring autophagy in a cell or subject and treating autophagy related diseases, such as cance...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG MINGJIE, ZHU RUICHI, WANG CHAO, LI JIANCHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides recombinant peptides useful for inhibiting the function of autophagy-related 8 (Atg8) proteins. The recombinant peptides can be used in the preparation of imaging agentsfor monitoring autophagy in a cell or subject and treating autophagy related diseases, such as cancer. 本文提供了可用于抑制自噬相关蛋白8(Atg8)的功能的重组肽。所述重组肽可用于制备成像剂，用于监测细胞或受试者中的自噬和治疗自噬相关疾病例如癌症。