Monoclonal antibody that specifically binds to GITR

The invention relates to biotechnology, in particular to an antibody or an antigen binding fragment thereof and application thereof. More specifically, the present invention relates to a monoclonal antibody that specifically binds to GITR. The present invention also relates to a nucleic acid encodin...

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Hauptverfasser:	GORDEV ALEXANDER ANDREYEVICH, BERNICEVA KSENIA MIHAILOVNA, DONONIN ALEXANDER NIKOLAYEVICH, KOZLOVA OLESYA NIKOLAEVNA, ISHUTINOVA ANASTASIA NIKOLAEVNA, IVANOV ROMAN ALEKSEYEVICH, SOZONOVA ALEXANDRA ALEXANDROVNA, ULITIN ANDREY BORISOVICH, MOROZOV DMITRY VALINKINOVICH, MITROSIN IVAN VLADIMIROVIC, SOLOVIEV VALERY VLADIMIROVIC, USCHUKOV YAKOV YURIVICH, AJEYEV SERGEY ANDREYEVICH, TSIMILOV VLADIMIR SERGEIVICH
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to biotechnology, in particular to an antibody or an antigen binding fragment thereof and application thereof. More specifically, the present invention relates to a monoclonal antibody that specifically binds to GITR. The present invention also relates to a nucleic acid encoding said antibody or antigen-binding fragment thereof, an expression vector, a method for preparing the antibody, and the use of said antibody in treatment GITR-associated diseases or disorders. 本发明涉及生物技术，尤其涉及抗体或其抗原结合片段及其用途。更具体说，本发明涉及与GITR特异性结合的单克隆抗体。本发明还涉及一种编码所述抗体或其抗原结合片段的核酸，一种表达载体，一种制备该抗体的方法，以及所述抗体在治疗GITR相关疾病或病症中的用途。