Tablet containing lamivudine and preparation method thereof

The invention discloses a tablet containing lamivudine. The tablet consists of the following components: lamivudine, a filler, a disintegrant, a lubricant and an adhesive, wherein the filler is selected from one or more of microcrystalline cellulose, lactose and mannitol; the disintegrant is selected from one or more of croscarmellose sodium, carboxymethyl starch sodium and crospovidone; the lubricant is magnesium stearate; the adhesive is selected from one or more of hydroxypropyl methylcellulose, povidone and hydroxypropyl cellulose. The invention also discloses a preparation method of lamivudine-containing tablets. According to the invention, reproducibility for the tablet preparation can be controlled by controlling the particle size range of the raw materials, the dissolution result consistent with the original research can be achieved, and fluctuation of the tablet is smaller than fluctuation of a reference product from the original research. In addition, the tablet crack rate of20 tablets of the invent